Glioblastomas (GBM) are primary brain tumors, meaning they arise from brain cells rather than traveling, or metastasizing, to the brain from other locations in the body. These tumors are aggressive and are able to grow quickly because the cells are supported by a large network of blood vessels. It is usually classified as high-grade, grades 3 and 4, because of their ability to grow rapidly.
Glioblastomas can cause increased pressure in the brain which presents as:
Other symptoms may include:
- Memory and/or speech difficulties
- Visual changes
Glioblastomas are managed with a combination of treatments including surgery, followed by radiation and chemotherapy. Surgical resection of the tumor reduces the amount of solid tumor tissue and radiation therapy selectively kills any remaining tumor cells.